Criteria for Nausea and Vomitting

Table 1. National Cancer Institute’s Common Terminology Criteria for Adverse Events: N&V^a

Adverse Event	Grade	Description
Nauseab	1	Loss of appetite without alteration in eating habits
	2	Oral intake decreased without significant weight loss, dehydration, or malnutrition
	3	Inadequate oral caloric or fluid intake; tube feeding, TPN, or hospitalization indicated
	4	Grade not available
	5	Grade not available
Vomitingc	1	1–2 episodes (separated by 5 min) in 24 h
	2	3–5 episodes (separated by 5 min) in 24 h
	3	≥6 episodes (separated by 5 min) in 24 h; tube feeding, TPN, or hospitalization indicated
	4	Life-threatening consequences; urgent intervention indicated
	5	Death

N&V = nausea and vomiting (emesis); TPN = total parenteral nutrition.

aAdapted from National Cancer Institute.[10]

bDefinition: A disorder characterized by a queasy sensation and/or the urge to vomit.

cDefinition: A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth.

References

10. National Cancer Institute.: Common Terminology Criteria for Adverse Events (CTCAE), Version 4.0. Bethesda, Md: U.S. Department of Health and Human Services, National Institutes of Health, 2010. Available online. Last accessed July 19, 2012.  
    

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